US researchers said on Wednesday they have identified antibodies that specifically protect against Zika virus infection in mice, an important step toward developing a vaccine, better diagnostic tests and possibly new antibody-based therapies. Get the Free Tracker App to find a SNES Classic in Stock Researchers at the Washington University School of Medicine in St. Louis made the achievement by infecting mice with Zika virus, which allowed the animals’ immune systems to produce anti-Zika antibodies, Xinhua news agency reported.Six antibodies were found, and from these, four were able to effectively prevent or treat Zika infection in cells and in mice, they reported in the US journal Cell.”Importantly, some of our antibodies are able to neutralize African, Asian and American strains of Zika virus to about the same degree,” Daved Fremont, a professor of pathology and immunology and a co-senior author on the paper, said in a statement.The study also showed that the antibodies bound exclusively to Zika and not to related viruses, which means they are specific enough to be used in diagnostic tests.Then, they used a technique called X-ray crystallography to zero in on the binding site and found the two most protective antibodies bound to the same region… Read full this story
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