UK Examines Whether Different COVID-19 Vaccines Can Be Used in 2-Shot Regimen

Testing began in Britain on Thursday to determine if different COVID-19 vaccines can be used together in a two-shot regimen. Researchers are aiming to inoculate more than 800 volunteers with one shot of the Pfizer-BioNTech vaccine, followed either four or 12 weeks later with a booster shot of the vaccine developed jointly by AstraZeneca and Oxford University, or vice versa. The vaccines were developed with different technology — the Pfizer vaccine through messenger RNA (mRNA), while the AstraZeneca-Oxford vaccine is adenovirus viral vector, or common cold virus. Health officials say if two vaccines developed with different technology are able to be used interchangeably, it could allow greater flexibility in immunization campaigns around the world. In a related development, The Guardian newspaper says an analysis of Israel's mass vaccination program has found that a single dose of the Pfizer-BioNTech vaccine provides 90% protection against the novel coronavirus by 21 days. Researchers at Britain's University of East Anglia contradict an earlier study from Israel that suggested one dose may not give adequate protection. Meanwhile, Oxford University says its COVID-19 vaccine is 76% effective at preventing infection for three months after a single dose. The findings were part of the same study released… Read full this story

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